姓 名:樊明文
性 别:男
出生年月:1939年4月
民 族:汉
籍 贯:湖北
毕业院校:四川大学华西口腔医学院
(原华西医科大学口腔系)
研究专业:口腔内科学
研究领域:龋病学、口腔生物学
兼职情况
中华口腔医学会副会长
湖北省医学会副会长
国务院学位委员会口腔学科评议组召集人
人民卫生出版社口腔医学教材编审委员会主任委员
国际牙科研究协会中国分会执行主席
国际牙科研究协会地区发展委员会委员
学术荣誉和荣誉称号
1991年起为国家级政府特殊津贴获得者
1992年被评为湖北省省管专家
1993年被评为湖北省有突出贡献中青年专家
1994年被评为国家级有突出贡献专家
1994年被评为全国省级医院优秀院长
1998年当选为第九届全国政协委员
2003年被评为武汉大学十大教学名师
在研科研项目:
项目名称 项目来源 起止时间 科研经费(万元)
成人牙髓干细胞的鉴定、分化特征及诱导牙髓再生的研究 教育部博士点基金 2002~2005 5
龋病预防和治疗的分子机制研究 武汉大学科创基金 2002~2005 8
DNA防龋疫苗及免疫防龋制剂研制及开发 省科技攻关计划 2002~2005 20
靶向融合防龋DNA疫苗的研制和粘膜免疫防龋的作用机制 国家自然科学基金面上项目 2002~2005 20
被动免疫防龋生物制品——特异性鸡蛋黄抗体喷雾 省科技攻关计划 2003~2005 5
靶向DNA疫苗激发粘膜免疫反应机制的研究 国家自然科学基金重点项目 2003~2006 120
中草药活性成份预防口腔疾病 省教委基金 2002~2005 6
靶向融合防龋DNA疫苗的临床前研究和开发 武汉市科技攻关计划 2006-2008 8
代表性论文 :
Jia Rong , Guo Jihua , Fan Mingwen* , Bian Zhuan , Chen Zhi , Fan Bing , Yu Fei, Xu Qingan . Immunogenicity of CTLA4 fusion anti-caries DNA vaccine in rabbits and monkeys. Vaccine , 2006 ;24:5192-5200
Shen Jing, Fan Mingwen*, Chen Xinming, Wang Shuozhi,Wang Li, Li Yuan. Glandular Odontogenic Cyst in China:Report of 12 Cases and Immunohistochemical Study. J Oral Pathology Medicine 2006, 35:175-82
Xu Qiong, Fan Mingwen*, Bing Fan , GSP Cheung , Hanlin Hu. A new quantitative method using glucose for analysis of endodontic leakage. Oral Surgery Oral Medicine Oral Pathology Oral Radiology Endodonitics 2005; 99:107-111
Xu Qing’an , Yu Fei , Fan Mingwen* , Bian Zhuan , Guo Jihua , Jia Rong ,. Chen Zhi , Peng Bin , Fan Bing . 2005 . Immunogenicity and protective efficacy of a targeted fusion DNA construct against dental caries . Caries Research 2005;39:422-431
Xue Jingling, Fan Mingwen*, Wang Shuozhi, Chen Xinming, Li Yuan, Wang Li. A clinical study of 674 patients with oral lichen planus in China. Journal of Oral Pathology Medicine 2005;34 (8): 467-472
Li Yuhong, Fan Mingwen*, Bian Zhuan, Chen Zhi, Peng Bing, Guo Jihua .Chitosan microparticles intended for anti-caries DNA vaccine mucosal delivery: synthesis, characterization and transfection. J Wuhan University of Technology, Materials Science Edition.2005;20(2):35-38
Li Yuhong, Fan Mingwen*, Bian Zhuan, Chen Zhi, Zhang Qi, Yang HR.Chitosan-DNA microparticles as mucosal delivery system: synthesis, release and distribution. Chinese Medical Journal .2005; 118 (11):936-941
Bing Fan, Gary S. P. Cheung, Mingwen Fan*, James L. Gutmann, Zhuan Bian. C-shaped Canal System in Mandibular Second Molars: Part-I—Anatomical Features. Jounal of Endodontics 2004;30:899-903
Bing Fan, Gary S. P. Cheung, Mingwen Fan*, James L. Gutmann and Wei Fan. C-shaped Canal System in Mandibular Second Molars: Part-II—Radiographic Feature. Jounal of Endodontics 2004;30:904-908
Rong Jia, Jihua Guo, Mingwen Fan*, Zhuan Bian, Zhi Chen, Bin Peng, Bing Fan. Mucosal immunization against dental caries with plasmid DNA encoding pac gene of Streptococcus mutans in rats. Vaccine 2004;22 2511–2516
Guo JH, Jia R, Fan MW*, Bian Z, Chen Z, Peng B..Construction and immunogenic characterization of a fusion anti-caries DNA vaccine against PAc and 2glucosyltransferase I of Streptococcus mutans . Journal of Dental Research 2004 ;83 (3): 266-270
Hongkun Wu, Mingwen Fan*, Xuedong Zhou, Anchun Mo, Zhuan Bian, Qi Zhang, Zhi Chen. Detection of Streptococcus mutans and Streptococcus sobrinus on the Permanent First Molars of the Mosuo People in China. Caries Research 2003;37:374-380
Mingwen. Fan*, Zhuan. Bian, Zhixiang. Peng, Yan. Zhong, Zhi. Chen, Bin. Peng, and Rong. Jia. A DNA Vaccine Encoding a Cell-surface Protein Antigen of Streptococcus mutans Protects Gnotobiotic Rats from Caries. J Dent Res 2002;81(11):784-787
Min Nie, Mingwen Fan*, Zhuan Bian. Transmission of mutans streptococci in adults within Chinese population. Caries Research. 2002;36(3):161-166
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